{"Abbreviation":"E2-TMA","Aliases":["Estradiol 17-pivalate","Estradiol, 17-pivalate","Estradiol monopivalate","Pivalic acid, 3-hydroxyestra-1,3,5(10)-trien-17β-yl ester","Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-(2,2-dimethylpropanoate)"],"CAS":"24894-50-6","ChemicalClasses":[],"Chirality":"absolute","EliminationHalfLife":"","Esters":[],"Formating":[],"HeavyAtomCount":26,"IUPACName":"[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 2,2-dimethylpropanoate","InChI":"InChI=1S/C23H32O3/c1-22(2,3)21(25)26-20-10-9-19-18-7-5-14-13-15(24)6-8-16(14)17(18)11-12-23(19,20)4/h6,8,13,17-20,24H,5,7,9-12H2,1-4H3/t17-,18-,19+,20+,23+/m1/s1","InChIKey":"SLOFBKMZOOTTDZ-WCZGSDDISA-N","MolecularFormula":"C\u003csub\u003e23\u003c/sub\u003eH\u003csub\u003e32\u003c/sub\u003eO\u003csub\u003e3\u003c/sub\u003e","MolecularWeight":"356.5 g/mol","Opticalactivity":"UNSPECIFIED","PubChemId":10522263,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Estradiol_pivalate","Name":"Estradiol pivalate","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q24884592","Name":"Estradiol pivalate","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/10522263","Name":"Estradiol pivalate","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=24894-50-6","Name":"Estradiol pivalate","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/I12U06L6S4","Name":"Estradiol pivalate","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID40179603","Name":"Estradiol pivalate","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 10522263, Estradiol pivalate. Accessed July 7, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/10522263\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/10522263\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Estradiol pivalate. UNII: I12U06L6S4. Global Substance Registration System. Accessed July 7, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/I12U06L6S4\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/I12U06L6S4\u003c/a\u003e"],"SMILES":"C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC(=O)C(C)(C)C)CCC4=C3C=CC(=C4)O","SaltData":[],"Salts":[],"Scheduling":[],"StereoisomerData":[],"Stereoisomers":["(+)-Estradiol pivalate","(-)-Estradiol pivalate"],"Structure":"\u003csvg  preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 140.611 101.23\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h141v102H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath stroke=\"none\" d=\"m85.913 52.39.696.073 3.331-14.974-2.089-.219-2.089-.219z\" class=\"bond\"/\u003e\u003cpath d=\"m86.261 52.427-13.107-7.62M73.154 44.807l-13.208 7.62\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M59.596 67.667h.7l1.9-16.942-2.25 1.297-1.969 1.137z\" class=\"bond\"/\u003e\u003cpath d=\"m59.946 67.667 13.208 7.62M73.154 75.287l13.107-7.62M86.261 52.427v15.24\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"m86.368 67.333-.214.667 13.733 6.176 1.253-1.723 1.352-1.858z\" class=\"bond\"/\u003e\u003cpath d=\"m100.79 72.34 8.94-12.293M109.73 60.047l-8.94-12.396M86.261 52.427l14.529-4.776\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"m100.457 47.543.666.217 4.694-10.278-1.558-.506-1.559-.507z\" class=\"bond\"/\u003e\u003cpath d=\"m109.128 32.386 11.278-2.397\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m120.841 28.65 8.007 8.893M119.029 30.282l8.007 8.893\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m128.848 37.543-4.003-4.447M127.036 39.175l-4.004-4.447\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m120.406 29.989 4.71-14.494M125.116 15.495l14.494 4.71M125.116 15.495l4.71-14.494M125.116 15.495l-14.494-4.71\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m72.851 75.461.607-.349M72.599 78.147l1.111-.641M72.346 80.833l1.617-.933M72.093 83.519l2.123-1.225M71.841 86.205l2.627-1.516M71.588 88.89l3.133-1.807M71.335 91.576l3.639-2.099\"/\u003e\u003c/g\u003e\u003cpath d=\"m73.154 90.527-13.208 7.62M59.946 98.147l-13.208-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M46.738 90.527v-15.24M44.3 89.118V76.695\"/\u003e\u003c/g\u003e\u003cpath d=\"m59.946 67.667-13.208 7.62M46.738 75.287l-13.208-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m33.53 67.667-13.208 7.62M33.53 70.482l-10.769 6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"M20.322 75.287v15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m20.322 90.527 13.208 7.62M22.761 89.118l10.769 6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"m46.738 90.527-13.208 7.62M20.322 90.527l-9.919 5.728\" class=\"bond\"/\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M107.759 33.154q0 .756-.256 1.328-.256.565-.756.881-.501.315-1.245.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881t1.274-.316q.732 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.459 0-.928-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.452M132.863 41.312q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.245-.571-.245-1.333 0-.75.245-1.31.25-.565.756-.881.506-.315 1.274-.315.732 0 1.232.315.5.31.756.875.256.566.256 1.328m-3.864 0q0 .923.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.535.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.453\" class=\"atom\"/\u003e\u003cg fill=\"#ff0d0d\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M9.385 98.146q0 .756-.256 1.327-.256.566-.756.881t-1.245.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881.506-.315 1.274-.315.733 0 1.233.315.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M4.305 100.598h-.62v-2.286H1.173v2.286H.56v-4.899h.613v2.072h2.512v-2.072h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m109.128 32.386 5.639-1.198M10.403 96.255l4.96-2.864M10.403 96.255l4.96-2.864\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Estradiol pivalate","UNII":"I12U06L6S4","Wikidata":"Q24884592","Wikipedia":"Estradiol_pivalate","XLogP":6}